Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing

10 Apr 2015

Abstract excerpt

Human ageing is associated with a gradual decline in the physiological functions of the body at multiple levels and it is a key risk factor for many diseases, including cancer. Ageing process is intimately related to widespread cellular senescence, characterised by an irreversible loss of proliferative capacity and altered functioning associated with telomere attrition, accumulation of DNA damage and compromised...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25847820
DOI: 10.1016/j.arr.2015.03.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageingPMID 25847820Read ↗

MicroRNAs as Mediators of the Ageing ProcessSemantic proximity Read ↗

The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular HallmarksSemantic proximity Read ↗

MicroRNA and Senescence: The Senectome, Integration and Distributed ControlSemantic proximity Read ↗

Impact of cellular senescence signature on ageing research.Semantic proximity Read ↗

From cellular senescence to age-associated diseases: the miRNA connectionSemantic proximity Read ↗

MicroRNA controls of cellular senescenceSemantic proximity Read ↗

Cellular Senescence - its role in cancer and the response to ionizing radiationSemantic proximity Read ↗

A Human Tissue-Specific Transcriptomic Analysis Reveals that Ageing Hinders Cancer and Boosts Cellular SenescenceSemantic proximity Read ↗

In brief: cell senescence.Semantic proximity Read ↗

Targeting cellular senescence to combat cancer and ageingSemantic proximity Read ↗

The Aging–Cancer Cycle: Mechanisms and Opportunities for InterventionSemantic proximity Read ↗

Cellular senescence, ageing and diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.