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A protein microarray-based <i>in vitro</i> transglutaminase assay platform for epitope mapping and immunogen design: implication for transglutaminase-mediated immunodominant determination

2021-05-13

Abstract excerpt

Transglutaminases (TGs) are a family of crosslinking enzymes catalyzing the formation of intra- and inter-molecular glutamine-lysine isopeptide bonds in a calcium dependent manner. Activation of transglutaminases is pathogenically associated with severe human diseases including neurodegenerations, cardiovascular diseases, and autoimmune diseases. Although continuous efforts determining the enzymes’ substrate prefe...

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Literature Corpus work
a14afbae-88d0-5f27-9e22-d2f0e7e83175
DOI
10.1101/2021.05.12.443622
Open publication

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A protein microarray-based <i>in vitro</i> transglutaminase assay platform for epitope mapping and immunogen design: implication for transglutaminase-mediated immunodominant determinationDOI 10.1101/2021.05.12.443622
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