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Article

The role of transglutaminase-2 and its substrates in human diseases.

Frontiers in bioscience : a journal and virtual library - 1 May 2006

Facchiano Francesco, Facchiano Antonio, Facchiano Angelo M

Abstract excerpt

The most characteristic enzymatic function of the class of enzymes known as transglutaminases (TG, EC 2.3.2.13) is the formation of covalent bonds between epsilon-amino groups of primary amines (from lysines or others) and the gamma-carboxamine group of glutamine residues of proteins. In the last years, a growing body of evidence indicate that the most interesting member of the TG family, namely the tissue TG...

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Identifiers

PMID: 16368554
DOI: 10.2741/1921

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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