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Article

Activation of hypothalamic RIP-Cre neurons promotes beiging of WAT via sympathetic nervous system.

EMBO reports - 1 Apr 2018

Wang Baile, Li Ang, Li Xiaomu, Ho Philip Wl, Wu Donghai, Wang Xiaoqi, Liu Zhuohao, Wu Kelvin Kl, Yau Sonata Sy, Xu Aimin, Cheng Kenneth Ky

Abstract excerpt

Activation of brown adipose tissue (BAT) and beige fat by cold increases energy expenditure. Although their activation is known to be differentially regulated in part by hypothalamus, the underlying neural pathways and populations remain poorly characterized. Here, we show that activation of rat-insulin-promoter-Cre (RIP-Cre) neurons in ventromedial hypothalamus (VMH) preferentially promotes recruitment of beige...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29467283
DOI: 10.15252/embr.201744977
PMCID: PMC5891405

Genes

APPL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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