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The Mediating Effect of 3-Methoxytyrosine on TWEAK Levels and Primary Sclerosing Cholangitis: A Genetic Perspective

2024-03-08

Abstract excerpt

<title>Abstract</title> <p>Primary sclerosing cholangitis (PSC) is a chronic liver disease characterized by inflammation, fibrosis, and bile stasis. Inflammatory proteins and metabolites may be involved in PSC pathogenesis. However, a comprehensive analysis is currently lacking. In this study, we employed a two-step Mendelian randomization (MR) analysis to quantify the proportion of the effect of metabolites-medi...

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Literature Corpus work
a109d1d9-a8c6-5d4f-953b-ac5dea3d54b7
DOI
10.21203/rs.3.rs-3993883/v1
Open publication

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The Mediating Effect of 3-Methoxytyrosine on TWEAK Levels and Primary Sclerosing Cholangitis: A Genetic PerspectiveDOI 10.21203/rs.3.rs-3993883/v1
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