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[Two-sample Mendelian randomization analysis for the causal relationship between 91 circulating inflammatory proteins and liver cirrhosis].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 20 Jun 2025

Li M, Zhou S J, Qiang L, Chen M, Tang Y, Wu G

Abstract excerpt

Objective: To analyze the causal relationship between circulating inflammatory proteins and the risk of liver cirrhosis by the two-sample Mendelian randomization (MR) method. Methods: Single nucleotide polymorphisms (SNP) strongly associated with 91 plasma inflammatory proteins in genome-wide association studies (GWAS) were used as instrumental variables, and liver cirrhosis was used as the outcome variable....

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Identifiers

PMID: 40660988
DOI: 10.3760/cma.j.cn501113-20241024-00555
PMCID: PMC12861756

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CD5

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