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Article

<i>Salmonella</i> effector kinase SteC is activated by host-mediated phosphorylation

2025-03-02

Abstract excerpt

<h4>SUMMARY</h4> The pathogen Salmonella , which causes significant human morbidity and mortality, encodes an effector kinase, SteC, which mediates actin polymerisation and cell migration. Given the minimal nature of its kinase domain, it remains unclear how SteC is catalytically active and how this activity is regulated. Here, we show that SteC is activated following the phosphorylation of the highly conserved...

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Literature Corpus work
a0f6bdee-c56c-538b-84e7-da095f579ed4
DOI
10.1101/2025.03.01.640964
Open publication

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<i>Salmonella</i> effector kinase SteC is activated by host-mediated phosphorylationDOI 10.1101/2025.03.01.640964
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