Article
Addressing the effects of Salmonella internalization in host cell signaling on a reverse-phase protein array.
Proteomics - 1 Jul 2009
Molero Cristina, Rodríguez-Escudero Isabel, Alemán Ainel, Rotger Rafael, Molina María, Cid Víctor J
Abstract excerpt
Through acute enteric infection, Salmonella invades host enterocytes and reproduces intracellularly into specialized vacuolae. This involves changes in host cell signaling elicited by bacterial proteins delivered via type III secretion systems (TTSS). One of the two TTSSs of Salmonella enterica serovar Typhimurium encoded by the Salmonella pathogenicity island-1, triggers bacterial internalization. Among the...
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