Article

Distinct STRIPAK subunits drive conserved and subunit-specific signaling programs in <i>Cryptococcus neoformans</i>

2026-01-05

Abstract excerpt

The striatin-interacting phosphatase and kinase (STRIPAK) complex is a conserved PP2A-associated signaling hub that integrates kinase-phosphatase networks, yet its roles in human fungal pathogens remain poorly defined. Here, we dissected STRIPAK functions in the opportunistic pathogen Cryptococcus neoformans by combining genetic, genomic, virulence, and phosphoproteomic analyses across mutants lacking individual...

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Literature Corpus work: 4b821a11-d820-5ba8-8a89-bfbe6c9abe9a
DOI: 10.64898/2026.01.05.697761

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