Article

miR-128 inhibits telomerase activity by targeting TERT mRNA

2017-10-06

Abstract excerpt

<h4>ABSTRACT</h4> Telomerase is a unique cellular reverse transcriptase essential for maintaining telomere stability and required for the unlimited proliferation of cancer cells. The limiting determinant of telomerase activity is the catalytic component TERT, and TERT expression is closely correlated with telomerase activity and cancer initiation and disease progression. For this reason the regulation of TERT lev...

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Literature Corpus work: a0f3b455-3cdc-5a2c-bb50-ddd2904d1cdb
DOI: 10.1101/195198

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