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Disruption of Reelin signaling in a dual-hit mouse model of schizophrenia: impact of postnatal Δ9-tetrahydrocannabinol exposure in a maternal immune activation model

2026-01-13

Abstract excerpt

<title>Abstract</title> <p>Since the discovery of the first antipsychotic, pharmacological treatment of schizophrenia (SCZ) has primarily relied on agents that block D2 dopamine receptors. However, due to variability in patient responses, there is a pressing need to identify new biomarkers and therapeutic strategies. In this context, we have developed a dual-hit mouse model that combines maternal immune activatio...

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Literature Corpus work
a0e0f0dc-a845-51ff-8dff-9cf21251008c
DOI
10.21203/rs.3.rs-7299003/v1
Open publication

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Disruption of Reelin signaling in a dual-hit mouse model of schizophrenia: impact of postnatal Δ9-tetrahydrocannabinol exposure in a maternal immune activation modelDOI 10.21203/rs.3.rs-7299003/v1
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