Article

Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth

2022-05-13

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron diseases affecting adults and infants, respectively. ALS and SMA are both characterized by the selective degeneration of motoneurons. Although different in their genetic etiology, growing evidence indicate that they share molecular and cellular pathogenic signatures that constitute potential common therapeutic targ...

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Literature Corpus work: a0bbf2c8-6a20-5361-bf8c-8c51038d5996
DOI: 10.1101/2022.05.12.491475

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