Article

A Rapid Gene Expression Profiler Classifies AML Tumor Responsiveness to Standard Therapies

2025-10-09

Abstract excerpt

The emergence of transcriptional signatures that define cell types and pathways has made it possible to guide cancer therapy selection through gene expression profiling. We developed a rapid qPCR-based platform to profile cell state, stemness, and BCL2 family gene expression as a companion diagnostic test for acute myeloid leukemia (AML). We validated the stability and utility of the signatures across multiple mea...

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Literature Corpus work: a095fd54-3897-5a6e-be4b-15d41f4ddafd
DOI: 10.1101/2025.10.08.681215

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