Article

The effects of reference panel perturbations on the accuracy of genotype imputation

2023-08-10

Abstract excerpt

Reference-based genotype imputation is a standard technique that has become increasingly popular in large-scale studies involving genomic data. The two key elements involved in the process of genotype imputation are (1) the haplotype reference panel to which a target individual is being imputed, and (2) the imputation algorithm used to infer missing genotypes in the target individual. The imputation literature has...

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Literature Corpus work: a07f29b0-c7be-5839-86e6-26541b19348e
DOI: 10.1101/2023.08.10.552684

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