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Article

On combining reference data to improve imputation accuracy.

PloS one - 1 Jan 2013

Chen Jun, Zhang Ji-Gang, Li Jian, Pei Yu-Fang, Deng Hong-Wen

Abstract excerpt

Genotype imputation is an important tool in human genetics studies, which uses reference sets with known genotypes and prior knowledge on linkage disequilibrium and recombination rates to infer un-typed alleles for human genetic variations at a low cost. The reference sets used by current imputation approaches are based on HapMap data, and/or based on recently available next-generation sequencing (NGS) data such...

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Identifiers

PMID: 23383238
DOI: 10.1371/journal.pone.0055600
PMCID: PMC3559437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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