Article

DNA hypomethylation during MSC chondrogenesis occurs predominantly at enhancer regions

2019-05-02

Abstract excerpt

<h4>Summary</h4> Regulation of transcription occurs in a cell type specific manner by epigenetic mechanisms including DNA methylation and histone modifications. Methylation changes during stem cell differentiation may play a key role in lineage specification. We sought to characterise DNA methylation changes during chondrogenesis of mesenchymal stem cells (MSCs) in order to further our understanding of epigenetic...

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Literature Corpus work: 9fcf833d-2a58-5f7f-9a13-d068b96a495d
DOI: 10.1101/625954

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