Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium–derived mesenchymal stem cells

29 Apr 2009

Abstract excerpt

OBJECTIVE: Human synovium-derived mesenchymal stem cells (MSCs) can efficiently differentiate into mature chondrocytes. It has been suggested that DNA methylation is one mechanism that regulates human chondrogenesis; however, the methylation status of genes related to chondrogenic differentiation is not known. The purpose of this study was to investigate the CpG methylation status in human synovium-derived MSCs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to Osteoarthritis Treatment and Mechanisms
Share to Tendon Structure and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19404940
DOI: 10.1002/art.24472

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium–derived mesenchymal stem cellsPMID 19404940Read ↗

DNA hypomethylation during MSC chondrogenesis occurs predominantly at enhancer regionsSemantic proximity Read ↗

Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cellsSemantic proximity Read ↗

Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoterSemantic proximity Read ↗

Early induction of a prechondrogenic population allows efficient generation of stable chondrocytes from human induced pluripotent stem cellsSemantic proximity Read ↗

Mesenchymal stem cells under epigenetic control – the role of epigenetic machinery in fate decision and functional propertiesSemantic proximity Read ↗

The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage qualitySemantic proximity Read ↗

The role of DNA methylation in chondrogenesis of human iPSCs as a stable marker of cartilage qualitySemantic proximity Read ↗

Genome-wide DNA methylation and multi-omics study of human chondrocyte ontogeny and an epigenetic clock analysis of adult chondrocytesSemantic proximity Read ↗

CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissuesSemantic proximity Read ↗

Prospective Isolation of Chondroprogenitors from Human iPSCs Based on Cell Surface Markers Identified using a CRISPR-Cas9-Generated ReporterSemantic proximity Read ↗

The long non-coding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cellsSemantic proximity Read ↗

HLA-G Expression in Human Mesenchymal Stem Cells (MSCs) Is Related to Unique Methylation Pattern in the Proximal Promoter as well as Gene Body DNASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.