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Article

DNA Methylation Profiling in Chondrocyte Dedifferentiation In Vitro.

Journal of cellular physiology - 1 Jul 2017

Duan Li, Liang Yujie, Ma Bin, Wang Daming, Liu Wei, Huang Jianghong, Xiong Jianyi, Peng Liangquan, Chen Jielin, Zhu Weimin, Wang Daping

Abstract excerpt

DNA methylation has emerged as a crucial regulator of chondrocyte dedifferentiation, which severely compromises the outcome of autologous chondrocyte implantation (ACI) treatment for cartilage defects. However, the full-scale DNA methylation profiling in chondrocyte dedifferentiation remains to be determined. Here, we performed a genome-wide DNA methylation profiling of dedifferentiated chondrocytes in monolayer...

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PMID: 27404036
DOI: 10.1002/jcp.25486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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