Article

Antidepressant-Induced Apathy in Adolescents with a Depressive Episode While Taking Sertraline: Results of 8-Week Observational Study with Pharmacogenetic Testing for <em>CYP2C19</em>

2025-11-21

Abstract excerpt

<h4>Objectives: </h4> To investigate the risk of developing emotional blunting in adolescents with a depressive episode who are prescribed sertraline. To establish associations of carriage of CYP2C19 gene polymorphisms with the antidepressant-induced apathy. Methods. The study included 133 adolescents (89.5% female) aged 12-17 who were prescribed sertraline. The follow-up was carried out for 8 weeks. Emotional blu...

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Literature Corpus work: 9f9af602-c499-5816-8f0d-eebc60a531af
DOI: 10.20944/preprints202511.1605.v1

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Antidepressant-Induced Apathy in Adolescents with a Depressive Episode While Taking Sertraline: Results of 8-Week Observational Study with Pharmacogenetic Testing for <em>CYP2C19</em>DOI 10.20944/preprints202511.1605.v1Read

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