Article

Sexual behaviour in a murine model of Mucopolysaccharidosis type I (MPS I)

2019-07-17

Abstract excerpt

Mucopolysaccharidosis Type I (MPS I) is a rare genetic lysosomal storage disease caused by a mutation of IDUA gene. IDUA codes for α-L-iduronidase (IDUA), a lysosomal hydrolase that degrades glycosaminoglycans (GAGs): heparan sulphate and dermatan sulphate. GAGs are structural and signalling molecules that have a crucial role in controlling a variety of cell functions and their interaction with extracellular mat...

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Literature Corpus work: 9f9a96fd-3b0e-59a2-adce-aa803821f7ca
DOI: 10.1101/705913

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