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Article

Development of motor deficits in a murine model of mucopolysaccharidosis type IIIA (MPS-IIIA).

Behavioural brain research - 30 Mar 2005

Hemsley Kim M, Hopwood John J

Abstract excerpt

Mucopolysaccharidosis (MPS) type IIIA or Sanfilippo syndrome is a lysosomal storage disorder characterised by progressive neurological pathology. Patients exhibit aggression, disturbed sleep, hyperactivity and mental decline ultimately resulting in inanition and death. Recently, a mouse model of MPS-IIIA was discovered, and both the clinical signs and neuropathological changes mimic the human disease. This...

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Identifiers

PMID: 15698885
DOI: 10.1016/j.bbr.2004.08.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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