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Article

Sexual behaviour in a murine model of mucopolysaccharidosis type I (MPS I).

PloS one - 1 Jan 2019

Barbosa Mendes Ana, do Nascimento Cinthia Castro, D'Almeida Vânia

Abstract excerpt

Mucopolysaccharidosis Type I (MPS I) is a rare genetic lysosomal storage disease caused by a mutation of IDUA gene. IDUA codes for α-L-iduronidase (IDUA), a lysosomal hydrolase that degrades glycosaminoglycans (GAGs): heparan sulphate and dermatan sulphate. GAGs are structural and signalling molecules that have a crucial role in controlling a variety of cell functions and their interaction with the extracellular...

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Identifiers

PMID: 31834922
DOI: 10.1371/journal.pone.0220429
PMCID: PMC6910675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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