Article

Activation of Kv11.1 potassium channel suppresses lung cancer growth by promoting c-Myc degradation.

2024-03-18

Abstract excerpt

<title>Abstract</title> <p>The Kv11.1 potassium channels and the transcription factor c-Myc both play fundamental roles in controlling cellular homeostasis. Cancers take advantage of dysregulated c-Myc and Kv11.1, however, little is known about the possible link between these proteins. In this work we found that an inverse relationship between c-MYC and Kv11.1 exists in some lung adenocarcinoma. Importantly, pati...

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Literature Corpus work: 9f6002c9-2e86-5ff6-99ab-1e4a71bd1aaa
DOI: 10.21203/rs.3.rs-3951965/v1

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