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Article

The influence of a caveolin-1 mutant on the function of P-glycoprotein.

Scientific reports - 4 Feb 2016

Lee Chih-Yuan, Lai Ting-Yu, Tsai Meng-Kun, Ou-Yang Pu, Tsai Ching-Yi, Wu Shu-Wei, Hsu Li-Chung, Chen Jin-Shing

Abstract excerpt

The genetic heterogeneity in cancer cells has an increased chance in the acquisition of new mutant such as drug-resistant phenotype in cancer cells. The phenotype of drug resistance in cancer cells could be evaluated by the number or function of drug transporters on cell membranes, which would lead to decreased intracellular anti-cancer drugs concentration. Caveolae are flask-shaped invaginations on cell membrane...

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Share to ATP Binding Cassette Transporter, Subfamily B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26843476
DOI: 10.1038/srep20486
PMCID: PMC4740904

Genes

CAV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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