Article

Identification of a High-frequency Intra-host SARS-CoV-2 spike Variant with Enhanced Cytopathic and Fusogenic Effect

2020-12-03

Abstract excerpt

<h4>ABSTRACT</h4> The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a virus that is continuously evolving. Although its RNA-dependent RNA polymerase exhibits some exonuclease proofreading activity, viral sequence diversity can be produced by replication errors and host factors. A diversity of genetic variants can be observed in the intra-host viral population structure of infected individuals. M...

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Literature Corpus work: 9f471ff4-5630-5399-a4c7-6c2ef894bf95
DOI: 10.1101/2020.12.03.409714

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