Article

Patient-derived mutations impact pathogenicity of SARS-CoV-2

2020-04-19

Abstract excerpt

<h4>Summary</h4> The sudden outbreak of the severe acute respiratory syndrome–coronavirus (SARS-CoV-2) has spread globally with more than 1,300,000 patients diagnosed and a death toll of 70,000. Current genomic survey data suggest that single nucleotide variants (SNVs) are abundant. However, no mutation has been directly linked with functional changes in viral pathogenicity. We report functional characterizations...

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Literature Corpus work: ed2f6169-2e0b-5c59-a7d5-11d40d1e7fdc
DOI: 10.1101/2020.04.14.20060160

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