Article

The loss of antioxidant activities impairs intestinal epithelium homeostasis by altering lipid metabolism

2023-03-09

Abstract excerpt

<h4>ABSTRACT</h4> The increase in reactive oxygens species (ROS) with aging could be at the origin of many diseases of the elderly. Here we investigated the role of ROS in the renewal of the intestinal epithelium in mice lacking catalase (CAT) and/or nicotinamide nucleotide transhydrogenase (NNT) activities. Cat -/- mice have delayed intestinal epithelium renewal and were prone to develop necrotizing enterocoli...

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Literature Corpus work: 9f32c92f-07b4-5749-a0d9-d2d01ee72a3f
DOI: 10.1101/2023.03.09.531979

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