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Article

Single-cell transcriptomics of blood reveals a natural killer cell subset depletion in tuberculosis

27 Feb 2020

Abstract excerpt

BACKGROUND: Tuberculosis (TB) continues to be a critical global health problem, which killed millions of lives each year. Certain circulating cell subsets are thought to differentially modulate the host immune response towards Mycobacterium tuberculosis (Mtb) infection, but the nature and function of these subsets is unclear. METHODS: Peripheral blood mononuclear cells (PBMC) were isolated from healthy controls...

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Identifiers

PMID: 32114394
DOI: 10.1016/j.ebiom.2020.102686

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