SGIV evades interferon immune response via the degradation of STING-TBK1 complex by VP149

Abstract excerpt

Singapore grouper iridovirus (SGIV), a highly pathogenic member of iridoviruses, has become a global threat in the aquaculture industry due to its economic losses and damage to ecological diversity worldwide. Recent reports have shown that SGIV inhibits host interferon (IFN) immune response induced by poly(I:C), however, the potential mechanisms for immune evasion remain largely uncertain. Here, VP149 protein enco...

Topics

Open a Topic to create a Post that cites this publication.

• Animal Virus Infections Studies
• Apoptosis
• Aquaculture disease management and microbiota
• interferon and immune responses
• Mosquito-borne diseases and control
• Viral Infections and Vectors
• Virology and Viral Diseases
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

9ec76eae-9aab-502f-9bb6-198f2aa7f795

DOI

10.1016/j.aquaculture.2024.740666