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Article

Negative regulation of the innate antiviral immune response by TRIM62 from orange spotted grouper

15 Aug 2016

Abstract excerpt

Increased reports uncovered that mammalian tripartite motif-containing 62 (TRIM62) exerts crucial roles in cancer and innate immune response. However, the roles of fish TRIM62 in antiviral immune response remained uncertain. In this study, a TRIM62 gene was cloned from orange spotted grouper (EcTRIM62) and its roles in grouper RNA virus infection was elucidated in vitro. EcTRIM62 shared 99% and 83% identity to...

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Identifiers

PMID: 27539706
DOI: 10.1016/j.fsi.2016.08.035

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