Article

Hijacking the transcriptional activation potential of the BAF complex via Induced Proximity

2023-12-18

Abstract excerpt

The BAF (Brg/Brahma-associated factors) complex, also referred to as the mammalian Switch/Sucrose-Nonfermentable (mSWI/SNF) chromatin remodeling complex, plays a pivotal role in epigenetically regulating diverse transcriptional programs. BAF’s chromatin remodeling activity, which enhances accessibility to transcriptional machinery, is critical for gene regulation. Recent studies have demonstrated that redirecting...

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Identifiers and source

Literature Corpus work: 9ea060dc-2c54-5535-a7d6-d3270f4f476c
DOI: 10.1101/2023.12.18.572217

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