Article

A post-inflammatory C3-high astrocyte state persists after inflammatory stimulus withdrawal and is attenuated by JAK inhibition

2026-05-28

Abstract excerpt

<h4>ABSTRACT</h4> Reactive astrocytes contribute to neuroinflammation and synaptic dysfunction, but it remains unclear whether transient inflammatory stimulation causes a persistent reactive state after the initial inflammatory stimulus is removed. Here, we investigated whether transient exposure to a defined inflammatory cytokine/complement cocktail induces a persistent reactive astrocyte state and examined the...

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Literature Corpus work: 9e8510df-8952-5dd8-b62b-69c3434d6969
DOI: 10.64898/2026.05.26.725945

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