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Article

ICOS enhances follicular T helper responses and deteriorates the pathogenic process of liver in mice infected with <i>Schistosoma japonicum</i>

2020-02-27

Abstract excerpt

<h4>Background</h4> Humoral immune responses play an important role in mediating liver granulomatous inflammation and fibrosis in schistosomiasis. Follicular helper T (Tfh) cells have a central role in mediating humoral immune responses. Generation of Tfh cells depends on inducible T cell costimulator (ICOS) signaling, but the underlying molecular mechanisms are incompletely understood in pathogenesis of schistos...

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Literature Corpus work
9e564469-ad0f-5055-9c62-72f92b3974c7
DOI
10.1101/2020.02.27.968248
Open publication

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