Article

JQ-1 ameliorates schistosomiasis liver fibrosis by suppressing JAK2 and STAT3 activation

2020-08-04

Abstract excerpt

Schistosomiasis is a serious parasitic infection caused by Schistosoma . The parasite deposits eggs in the host liver, causing inflammation that activates hepatic stellate cells (HSCs), which leads to liver fibrosis. Currently, there is no effective therapy for liver fibrosis; thus, treatments are urgently needed. Therefore, in the present study, mice infected with Schistosoma japonicum were treated with JQ-1, a...

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Literature Corpus work: 7230e61a-47aa-5d4c-bb5f-2f3f91ca0dd3
DOI: 10.1101/2020.08.04.235812

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