Article

CD8 <sup>+</sup> T-cell transcription and DNA methylation show age specific differences and lack correlation with clinical outcome in pediatric Inflammatory Bowel Disease

2020-03-31

Abstract excerpt

<h4>Background & Aims</h4> CD8 + T-cell gene expression has been implicated in the pathogenesis of Inflammatory Bowel Diseases (IBD) and has been shown to correlate with disease outcome in adult patients. Moreover, CD8 + T-cell exhaustion was identified as a contributing mechanism that impacts on disease behaviour. We aimed to explore CD8 + T-cell gene expression and DNA methylation in children newly diagnosed...

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Literature Corpus work: 9dfaf8ce-7c81-59e5-9cf3-c2f956949321
DOI: 10.1101/2020.03.30.015446

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CD8 <sup>+</sup> T-cell transcription and DNA methylation show age specific differences and lack correlation with clinical outcome in pediatric Inflammatory Bowel DiseaseDOI 10.1101/2020.03.30.015446Read

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