Article

High CD38 expression defines a mitochondrial function adapted CD8 + T cell subset with implications for lung cancer immunotherapy

2024-08-28

Abstract excerpt

<title>Abstract</title> Despite identifying specific CD8+T cell subsets associated with immunotherapy resistance, the molecular pathway triggering the process remains elusive. Given the potential of CD38 in regulating CD8+T cell function, we aimed to observe the accumulation of CD38+CD8+T cells in lung cancer and further explored its role in immunotherapy resistance....

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Literature Corpus work: 9debd97f-6a45-557d-beb8-ad22fbc09eab
DOI: 10.21203/rs.3.rs-4815459/v1

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