Article

Spatial distribution of PD-1+CD39+CD8+ T cell in TME refined its tumorigenic and immunotherapeutic biomarker in lung cancer

2022-12-20

Abstract excerpt

<h4>Purpose: </h4> CD8 + T cells in tumors are heterogenous and comprise multiple differentiation states. It has been reported that human tumor-infiltrating CD8 + T cells can express CD39 and more evidences proposed CD39 as a marker of exhausted and tumor reactive CD8 + T cells. However, no studies have delved into the spatial distribution of the CD39 + CD8 + T cell subsets in lung cancer, which could help to eval...

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Literature Corpus work: 155d8782-8a0b-5cce-871e-dc6ee4ff71f5
DOI: 10.21203/rs.3.rs-2347885/v1

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