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DNA methylation regulator-mediated modification pattern defines tumor microenvironment immune infiltration landscape in colon cancer

6 Oct 2022

Abstract excerpt

Emerging evidence implies a non-negligible role of DNA methylation in tumor immunity, however, its comprehensive impact on tumor microenvironment (TME) formation and immune activation remains unclear. In this study, we integrated 24 DNA methylation regulators among 754 colon cancer patients to distinguish different modification patterns via an unsupervised clustering method, and explore their TME immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36276973
DOI: 10.3389/fgene.2022.1008644

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