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Article

DNA Methylation Modification Map to Predict Tumor Molecular Subtypes and Efficacy of Immunotherapy in Bladder Cancer

3 Dec 2021

Abstract excerpt

Background: Considering the heterogeneity and complexity of epigenetic regulation in bladder cancer, the underlying mechanisms of global DNA methylation modification in the immune microenvironment must be investigated to predict the prognosis outcomes and clinical response to immunotherapy. Methods: We systematically assessed the DNA methylation modes of 985 integrated bladder cancer samples with the unsupervised...

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Share to Bladder and Urothelial Cancer Treatments
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Identifiers

PMID: 34926451
DOI: 10.3389/fcell.2021.760369

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