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m6A regulator-mediated methylation modification patterns and tumor microenvironment infiltration characterization in gastric cancer

12 Mar 2020

Abstract excerpt

Abstract Background The epigenetic regulation of immune response has been demonstrated in recent studies. Nonetheless, potential roles of RNA N6-methyladenosine (m 6 A) modification in tumor microenvironment (TME) cell infiltration remain unknown. Methods We comprehensively evaluated the m 6 A modification patterns of 1938 gastric cancer samples based on 21 m 6 A regulators, and systematically correlated these...

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PMID: 32164750
DOI: 10.1186/s12943-020-01170-0

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