Article

Viral apoptosis evasion via the MAPK pathway by use of a host long noncoding RNA

2017-06-21

Abstract excerpt

<h4>SUMMARY</h4> An emerging realisation of infectious disease is the high incidence of genetic instability resulting from pathogen-induced DNA lesions, often leading to classical hallmarks of cancer such as evasion of apoptosis. The Human Immunodeficiency Virus type 1 (HIV-1) induces apoptosis in CD4+ T cells but is largely non-cytopathic in macrophages, thereby leading to long-term dissemination of the pathogen...

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Literature Corpus work: 9de042ba-c5d1-5bd1-bd26-0c1edc1a286d
DOI: 10.1101/153130

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