Article

Activation of NIX-mediated mitophagy and replication by an interferon regulatory factor homologue of human herpesvirus

2018-12-25

Abstract excerpt

Viral control of mitochondrial quality and content has emerged as an important mechanism for counteracting the host response to virus infection. Despite the knowledge of this crucial function of some viruses, little is known about how herpesviruses regulate mitochondrial homeostasis during infection. Human herpesvirus 8 (HHV-8) is an oncogenic virus causally related to AIDS-associated malignancies. Here, we found...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1e66ac8a-fc4f-5c0f-9fb3-cb27f34ef939
DOI: 10.1101/506113

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Activation of NIX-mediated mitophagy and replication by an interferon regulatory factor homologue of human herpesvirusDOI 10.1101/506113Read

Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirusSemantic proximity Read

The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagySemantic proximity Read

Modulation of Mitochondrial Antiviral Signaling by Human Herpesvirus 8 Interferon Regulatory Factor 1Semantic proximity Read

Viral strategies for triggering and manipulating mitophagySemantic proximity Read

Mitophagy in Antiviral ImmunitySemantic proximity Read

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complexSemantic proximity Read

The Role of Mitophagy in Viral InfectionSemantic proximity Read

Crosstalk between mitophagy and innate immunity in viral infectionSemantic proximity Read

The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagySemantic proximity Read

Kaposi’s sarcoma-associated herpesvirus induces mitochondrial fission to evade host immune responses and promote viral productionSemantic proximity Read

Bunyavirus SFTSV nucleoprotein exploits TUFM-mediated mitophagy to impair antiviral innate immunitySemantic proximity Read

The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cellsSemantic proximity Read