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Article

Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus

19 Jul 2019

Abstract excerpt

Viral control of mitochondrial quality and content has emerged as an important mechanism for counteracting the host response to virus infection. Despite the knowledge of this crucial function of some viruses, little is known about how herpesviruses regulate mitochondrial homeostasis during infection. Human herpesvirus 8 (HHV-8) is an oncogenic virus causally related to AIDS-associated malignancies. Here, we show...

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PMID: 31324791
DOI: 10.1038/s41467-019-11164-2

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