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Modulation of apoptosis and viral latency – an axis to be well understood for successful cure of human immunodeficiency virus

13 Jan 2016

Abstract excerpt

Human immunodeficiency virus (HIV) is the causative agent of the deadly disease AIDS, which is characterized by the progressive decline of CD4(+)T-cells. HIV-1-encoded proteins such as envelope gp120 (glycoprotein gp120), Tat (trans-activator of transcription), Nef (negative regulatory factor), Vpr (viral protein R), Vpu (viral protein unique) and protease are known to be effective in modulating host cell...

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PMID: 26764023
DOI: 10.1099/jgv.0.000402

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