Article

Selective inhibition of microRNA processing by a herpesvirus-encoded microRNA triggers virus reactivation from latency

2021-09-03

Abstract excerpt

<title>Abstract</title> <p>Herpesviruses have mastered host cell modulation and immune evasion to augment productive infection, life-long latency and reactivation thereof 1,2. A long appreciated, yet elusively defined relationship exists between the lytic-latent switch and viral non-coding RNAs 3,4. Here, we identify miRNA-mediated inhibition of miRNA processing as a novel cellular mechanism that human herpesviru...

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Literature Corpus work: 3ca81048-9be1-5590-ae59-78675b8f4c7c
DOI: 10.21203/rs.3.rs-820696/v1

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