Article

Bias amplification of unobserved confounding in pharmacoepidemiological studies using indication-based sampling: there is no free lunch in restricting the sample to those with a particular drug-indication

2022-02-08

Abstract excerpt

Estimating causal effects in observational pharmacoepidemiology is a challenging task, as it is often plagued by confounding by indication. Restricting the sample to those with an indication for drug use is a commonly performed procedure; indication-based sampling ensures that the exposed and unexposed are exchangeable on the indication - limiting the potential for confounding by indication. However, indication-ba...

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Literature Corpus work: 9da90621-00aa-5545-b8b3-97b4c5d80af6
DOI: 10.1101/2022.02.07.22270609

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Bias amplification of unobserved confounding in pharmacoepidemiological studies using indication-based sampling: there is no free lunch in restricting the sample to those with a particular drug-indicationDOI 10.1101/2022.02.07.22270609Read

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