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Article

Internal pilots for observational studies.

Biometrical journal. Biometrische Zeitschrift - 1 Oct 2010

Gurka Matthew J, Coffey Christopher S, Gurka Kelly K

Abstract excerpt

Study planning often involves selecting an appropriate sample size. Power calculations require specifying an effect size and estimating "nuisance" parameters, e.g. the overall incidence of the outcome. For observational studies, an additional source of randomness must be estimated: the rate of the exposure. A poor estimate of any of these parameters will produce an erroneous sample size. Internal pilot (IP)...

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Identifiers

PMID: 20857422
DOI: 10.1002/bimj.201000050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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