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Article

Critical COVID-19 is associated with distinct leukocyte phenotypes and transcriptome patterns.

Journal of internal medicine - 1 Sept 2021

Christensen E E, Jørgensen M J, Nore K G, Dahl T B, Yang K, Ranheim T, Huse C, Lind A, Nur S, Stiksrud B, Jenum S, Tonby K, Holter J C, Holten A R, Halvorsen B, Dyrhol-Riise A M

Abstract excerpt

BACKGROUND: Prognostic markers for disease severity and identification of therapeutic targets in COVID-19 are urgently needed. We have studied innate and adaptive immunity on protein and transcriptomic level in COVID-19 patients with different disease severity at admission and longitudinally during hospitalization. METHODS: Peripheral blood mononuclear cells (PBMCs) were collected at three time points from 31...

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Identifiers

PMID: 34080738
DOI: 10.1111/joim.13310
PMCID: PMC8242786

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