Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Longitudinal whole blood transcriptomic analysis characterizes neutrophil activation and interferon signaling in moderate and severe COVID-19

26 Jun 2023

Abstract excerpt

A maladaptive inflammatory response has been implicated in the pathogenesis of severe COVID-19. This study aimed to characterize the temporal dynamics of this response and investigate whether severe disease is associated with distinct gene expression patterns. We performed microarray analysis of serial whole blood RNA samples from 17 patients with severe COVID-19, 15 patients with moderate disease and 11 healthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to Immune responses and vaccinations
Share to Long-Term Effects of COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37365222
DOI: 10.1038/s41598-023-37606-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Longitudinal whole blood transcriptomic analysis characterizes neutrophil activation and interferon signaling in moderate and severe COVID-19PMID 37365222Read ↗

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.Semantic proximity Read ↗

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patientsSemantic proximity Read ↗

ScRNA-Seq study of neutrophils reveals vast heterogeneity and breadth of inflammatory responses in severe COVID-19 patientsSemantic proximity Read ↗

Characterisation of the blood RNA host response underpinning severity in COVID-19 patientsSemantic proximity Read ↗

Characterisation of the blood RNA host response underpinning severity in COVID-19 patientsSemantic proximity Read ↗

Severe COVID-19 Shares a Common Neutrophil Activation Signature with Other Acute Inflammatory StatesSemantic proximity Read ↗

Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory statesSemantic proximity Read ↗

Upregulated type I interferon responses in asymptomatic COVID-19 infection are associated with improved clinical outcomeSemantic proximity Read ↗

Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patientsSemantic proximity Read ↗

Suppressive myeloid cells are a hallmark of severe COVID-19Semantic proximity Read ↗

Multi-Omics Profiling Reveals Phenotypic and Functional Heterogeneity of Neutrophils in COVID-19.Semantic proximity Read ↗

CD177, a specific marker of neutrophil activation, is a hallmark of COVID-19 severity and deathSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.