Back to search

Article

Temporal proteomic and PTMomic atlas of cerebral organoid development

2024-09-03

Abstract excerpt

Cerebral organoids (CBOs) are generated from pluripotent stem cells that undergo neuroectoderm specification and neuronal differentiation in three dimensions. The developing neurons in CBOs migrate and self-organize into cerebral cortex-like layers, mimicking human brain development. CBOs develop according to intrinsic signaling mechanisms and offer unique insights into mechanisms of early human brain development....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6c431769-a916-5281-a13e-25dde7818ce2
DOI
10.1101/2024.09.03.610941
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Temporal proteomic and PTMomic atlas of cerebral organoid developmentDOI 10.1101/2024.09.03.610941
Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profilesSemantic proximity
Proteome Complexity Scales with Architecture in Human Neural ModelsSemantic proximity
Single Cell Proteomics in the Developing Human BrainSemantic proximity
Single-cell multiomics atlas of organoid development uncovers longitudinal molecular programs of cellular diversification of the human cerebral cortexSemantic proximity
Dynamic proteomic and phosphoproteomic atlas of corticostriatal axon neurodevelopmentSemantic proximity
Benchmarking brain organoid recapitulation of fetal corticogenesisSemantic proximity
Multi-omics identification of extracellular components of the fetal monkey and human neocortexSemantic proximity
The RNA and protein landscapes of mouse brain organoidsSemantic proximity
The Proteomic Architecture of Schizophrenia Cerebral Organoids Reveals Alterations in GWAS and Neuronal Development FactorsSemantic proximity
Optimizing PSC culture for generating neural organoidsSemantic proximity
A consensus atlas of human brain development defines cell type-specific maturation trajectories across the lifespanSemantic proximity
Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellumSemantic proximity
Select a neighboring publication to make it the new centre.